REV. A
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AD8225
Precision Gain of 5
Instrumentation Amplifier
FEATURES
No External Components Required
Highly Stable, Factory Trimmed Gain of 5
Low Power, 1.2 mA Max Supply Current
Wide Power Supply Range (1.7 V to 18 V)
Single- and Dual-Supply Operation
Excellent Dynamic Performance
High CMRR
86 dB Min @ DC
80 dB Min to 10 kHz
Wide Bandwidth
900 kHz
4 V to 36 V Single Supply
High Slew Rate
5 V/s Min
Outstanding DC Precision
Low Gain Drift
5 ppm/C Max
Low Input Offset Voltage
150 V Max
Low Offset Drift
2 V/C Max
Low Input Bias Current
1.2 nA Max
APPLICATIONS
Patient Monitors
Current Transmitters
Multiplexed Systems
4 to 20 mA Converters
Bridge Transducers
Sensor Signal Conditioning
FUNCTIONAL BLOCK DIAGRAM
8
7
6
5
1
2
3
4
NC = NO CONNECT
NC
–IN
+IN
–VS
NC
+VS
VOUT
REF
AD8225
GENERAL DESCRIPTION
The AD8225 is an instrumentation amplifier with a fixed gain
of 5, which sets new standards of performance. The superior
CMRR of the AD8225 enables rejection of high frequency
common-mode voltage (80 dB Min @ 10 kHz). As a result,
higher ambient levels of noise from utility lines, industrial
equipment, and other radiating sources are rejected. Extended
CMV range enables the AD8225 to extract low level differential
signals in the presence of high common-mode dc voltage levels
even at low supply voltages.
Ambient electrical noise from utility lines is present at 60 Hz
and harmonic frequencies. Power systems operating at 400 Hz
create high noise environments in aircraft instrument clusters.
Good CMRR performance over frequency is necessary if power
system generated noise is to be rejected. The dc to 10 kHz
FREQUENCY – Hz
140
1 100k10
CMRR – dB
100 1k 10k
130
120
110
100
90
80
70
60
50
40
30
HIGH PERFORMANCE IN AMP
@ GAIN OF 5
AD8225
Figure 1. Typical CMRR vs. Frequency
CMRR performance of the AD8225 rejects noise from utility
systems, motors, and repair equipment on factory floors, switch-
ing power supplies, and medical equipment.
Low input bias currents combined with a high slew rate of 5 V/µs
make the AD8225 ideally suited for multiplexed applications.
The AD8225 provides excellent dc precision, with maximum
input offset voltage of 150 µV and drift of 2 µV/°C. Gain drift is
5 ppm/°C or less.
Operating on either single or dual supplies, the fixed gain of 5
and wide input common-mode voltage range make the AD8225
well suited for patient monitoring applications.
The AD8225 is packaged in an 8-lead SOIC package and is
specified over the standard industrial temperature range, 40°C
to +85°C.
REV. A–2–
AD8225–SPECIFICATIONS
(TA = 25C, VS = 15 V, RL = 2 k, unless otherwise noted.)
Parameter Conditions Min Typ Max Unit
GAIN
Gain 5V/V
Gain Error 0.1 +0.05 +0.1 %
Nonlinearity 2 10 ±ppm
vs. Temperature 1 5 ±ppm/°C
OFFSET VOLTAGE (RTI)
Offset Voltage 50 150 ±µV
vs. Temperature 0.3 2 ±µV/°C
vs. Supply (PSRR) 90 100 dB
INPUT
Input Operating Impedance
Differential 10
2G
pF
Common Mode 10
2G
pF
Input Voltage Range V
S
+ 1.6 +V
S
1.0 V
(Common-Mode)
vs. Temperature V
S
+ 2.2 +V
S
1.2 V
Input Bias Current 0.5 1.2 nA
vs. Temperature 3 pA/°C
Input Offset Current 0.15 0.5 nA
vs. Temperature 1.5 pA/°C
Common-Mode Rejection Ratio 86 94 dB
T
A
= T
MIN
to T
MAX
83 dB
f = 10 kHz*80 dB
OUTPUT
Operating Voltage Range R
L
= 2 kV
S
+ 1.4 +V
S
1.4 V
vs. Temperature V
S
+ 1.5 +V
S
1.6 V
Operating Voltage Range R
L
= 10 kV
S
+ 1.0 +V
S
1.1 V
vs. Temperature V
S
+ 1.2 +V
S
1.0 V
Short Circuit Current 18 mA
DYNAMIC RESPONSE
Small Signal 3 dB Bandwidth 900 kHz
Full Power Bandwidth V
OUT
= 20 V p-p 75 kHz
Settling Time (0.01%) 10 V Step 3.4 µs
Settling Time (0.001%) 10 V Step 4.8 µs
Slew Rate 5 V/µs
NOISE (RTI)
Voltage 0.1 Hz to 10 Hz 1.5 µV p-p
Spectral Density, 1 kHz 45 nV/Hz
Current 0.1 Hz to 10 Hz 4 pA p-p
Spectral Density, 1 kHz 50 fA/Hz
REFERENCE INPUT
R
IN
V
IN+
, V
REF
= 0 18 k
I
IN
60 µA
Voltage Range V
S
+ 1.4 +V
S
1.4 V
Gain to Output 0.999 1 1.001
POWER SUPPLY
Operating Range 1.7 18 ±V
Quiescent Current 1.05 1.2 mA
TEMPERATURE RANGE
For Specified Performance 40 +85 °C
*Pin 1 connected to Pin 4. See Applications section.
Specifications subject to change without notice.
REV. A
AD8225
–3–
Parameter Conditions Min Typ Max Unit
GAIN
Gain 5V/V
Gain Error 0.1 +0.05 +0.1 %
Nonlinearity 2 10 ±ppm
vs. Temperature 1 5 ±ppm/°C
VOLTAGE OFFSET (RTI)
Offset Voltage 125 325 ±µV
vs. Temperature 2±µV/°C
vs. Supply 90 100 dB
INPUT
Input Operating Impedance
Differential 10
2G
pF
Common-Mode 10
2G
pF
Input Operating Voltage Range V
S
+ 1.6 +V
S
1.0 V
vs. Temperature V
S
+ 2.1 +V
S
1.5 V
Input Bias Current 0.5 1.2 nA
vs. Temperature 3 pA/°C
Input Offset Current 0.15 0.5 nA
vs. Temperature 1.5 pA/°C
Common-Mode Rejection Ratio 86 94 dB
T
A
= T
MIN
to T
MAX
83 dB
f = 10 kHz*80 dB
OUTPUT
Operating Voltage Range R
L
= 2 kV
S
+ 0.9 +V
S
1.0 V
vs. Temperature V
S
+ 1.0 +V
S
1.2 V
Operating Voltage Range R
L
= 10 kV
S
+ 0.8 +V
S
1.0 V
vs. Temperature V
S
+ 0.9 +V
S
1.0 V
Short Circuit Current 18 mA
DYNAMIC RESPONSE
Small Signal 3 dB Bandwidth 900 kHz
Full Power Bandwidth V
OUT
= 7.8 V p-p 170 kHz
Settling Time (0.01%) 7 V Step 3 µs
Settling Time (0.001%) 7 V Step 4.3 µs
Slew Rate 5 V/µs
NOISE (RTI)
Voltage 0.1 Hz to 10 Hz 1.5 µV p-p
Spectral Density, 1 kHz 45 nV/Hz
Current 0.1 Hz to 10 Hz 4 pA p-p
Spectral Density, 1 kHz 50 fA/Hz
REFERENCE INPUT
R
IN
18 k
I
IN
V
INT
, V
REF
= 0 60 µA
Voltage Range V
S
+ 0.9 +V
S
1.0 V
Gain to Output 0.999 1 1.001
POWER SUPPLY
Operating Range 1.7 18 ±V
Quiescent Current 1.05 1.2 mA
TEMPERATURE RANGE
For Specified Performance 40 +85 °C
*Pin 1 connected to Pin 4. See Applications section.
Specifications subject to change without notice.
SPECIFICATIONS
(TA = 25C, VS = 5 V, RL = 2 k, unless otherwise noted.)
REV. A–4–
AD8225
Parameter Conditions Min Typ Max Unit
GAIN
Gain 5V/V
Gain Error 0.1 +0.05 +0.1 %
Nonlinearity 2 10 ±ppm
vs. Temperature 1 5 ±ppm/°C
OFFSET VOLTAGE (RTI)
Offset Voltage 150 375 ±µV
vs. Temperature 2±µV/°C
vs. Supply 90 100 dB
INPUT
Input Operating Impedance
Differential 10
2G
pF
Common Mode 10
2G
pF
Input Voltage Range 1.6 V
S
1.05 V
(Common-Mode)
vs. Temperature 1.7 V
S
1.0 V
Input Bias Current 0.5 1.2 nA
vs. Temperature 3 pA/°C
Input Offset Current 0.15 0.5 nA
vs. Temperature 1.5 pA/°C
Common-Mode Rejection Ratio 86 94 dB
T
A
= T
MIN
to T
MAX
83 dB
f = 10 kHz*80 dB
OUTPUT
Operating Voltage Range R
L
= 2 k0.8 V
S
1.05 V
vs. Temperature 0.9 V
S
1.2 V
Operating Voltage Range R
L
= 10 k0.8 V
S
1.0 V
vs. Temperature 0.9 V
S
1.0 V
Short Circuit Current 18 mA
DYNAMIC RESPONSE
Small Signal 3 dB Bandwidth 900 kHz
Full Power Bandwidth V
OUT
= 3.2 V p-p 420 kHz
Settling Time (0.01%) 2 V Step 3.3 µs
Settling Time (0.001%) 2 V Step 5.1 µs
Slew Rate 5 V/µs
NOISE (RTI)
Voltage 0.1 Hz to 10 Hz 1.5 µV p-p
Spectral Density, 1 kHz 45 nV/Hz
Current 0.1 Hz to 10 Hz 4 pA p-p
Spectral Density, 1 kHz 50 fA/Hz
REFERENCE INPUT
R
IN
18 k
I
IN
60 µA
Voltage Range 0.4 V
S
0.9 V
Gain to Output 0.999 1 1.001
POWER SUPPLY
Operating Range 3.4 36 V
Quiescent Current 1.05 1.2 mA
TEMPERATURE RANGE
For Specified Performance 40 +85 °C
*Pin 1 connected to Pin 4. See Applications section.
Specifications subject to change without notice.
SPECIFICATIONS
(TA = 25C, VS = 5 V, RL = 2 k, unless otherwise noted.)
REV. A
AD8225
–5–
PIN FUNCTION DESCRIPTIONS
Pin Number Mnemonic Function
1NCMay be Connected to Pin 4 to
Balance C
IN
2IN Inverting Input
3+IN Noninverting Input
4V
S
Negative Supply Voltage
5REF Connect to Desired Output
CMV
6V
OUT
Output
7+V
S
Positive Supply Voltage
8NC
ABSOLUTE MAXIMUM RATINGS*
Supply Voltage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ±18 V
Internal Power Dissipation . . . . . . . . . . . . . . . . . . . . 650 mW
Input Voltage (Common-Mode) . . . . . . . . . . . . . . . . . . . . ±V
S
Differential Input Voltage . . . . . . . . . . . . . . . . . . . . . . . ±25 V
Output Short Circuit Duration . . . . . . . . . . . . . . . . Indefinite
Storage Temperature . . . . . . . . . . . . . . . . . . 65ºC to +125ºC
Operating Temperature Range . . . . . . . . . . . 40ºC to +85ºC
Lead Temperature Range (10 sec Soldering) . . . . . . . . . 300ºC
*Stresses above those listed under Absolute Maximum Ratings may cause perma-
nent damage to the device. This is a stress rating only and functional operation of
the device at these or any other conditions above those indicated in the operational
section of this specification is not implied. Exposure to absolute maximum rating
conditions for extended periods may affect device reliability.
AMBIENT TEMPERATURE – C
1.5
1.0
0
–50 80
–40
POWER DISSIPATION – W
–30 –20 –10 0 10 203040506070
0.5
90
TJ = 150 C
8-LEAD SOIC PACKAGE
Figure 2. Maximum Power Dissipation vs. Temperature
ORDERING GUIDE
Model Temperature Range Package Description Package Options
AD8225AR 40ºC to +85ºC 8-Lead SOIC RN-8
AD8225AR-REEL 40ºC to +85ºC8-Lead SOIC 13" REEL
AD8225AR-REEL7 40ºC to +85ºC8-Lead SOIC 7" REEL
AD8225-EVAL Evaluation Board RN-8
CAUTION
ESD (electrostatic discharge) sensitive device. Electrostatic charges as high as 4000 V readily
accumulate on the human body and test equipment and can discharge without detection. Although the
AD8225 features proprietary ESD protection circuitry, permanent damage may occur on devices
subjected to high energy electrostatic discharges. Therefore, proper ESD precautions are recommended
to avoid performance degradation or loss of functionality.
REV. A–6–
AD8225–Typical Performance Characteristics
INPUT OFFSET VOLTAGE – V
50
20
0
–140 120–120
% OF UNITS
–80 –40 –20 0 20 40 60 80
45
25
15
5
35
30
10
40
LOT SIZE = 3775
–100 –60 100
TPC 1. Typical Distribution of Input Offset Voltage,
V
S
=
±
15 V
INPUT BIAS CURRENT – pA
50
20
0
–200 800–100
% OF UNITS
0 100 200 300 400 500 700
45
25
15
5
35
30
10
40
LOT SIZE = 7550
600
TPC 2. Typical Distribution of Input Bias Current,
V
S
=
±
15 V
INPUT OFFSET CURRENT – pA
50
20
0
–500 400–400
% OF UNITS
–300 –100 0 100 200 300
45
25
15
5
35
30
10
40
LOT SIZE = 3775
–200
TPC 3. Typical Distribution of Input Offset Current,
V
S
=
±
15 V
TEMPERATURE – C
250
–50
–60 100–40
BIAS CURRENT – pA
–20 0 20 40 60 80
200
150
100
50
0
+BIAS CURRENT
–BIAS CURRENT
TPC 4. Bias Current vs. Temperature
WARM-UP TIME – Min
8
6
0051
CHANGE IN OFFSET VOLTAGE – V
234
4
2
TPC 5. Offset Voltage vs. Warm-Up Time
FREQUENCY – Hz
1000
100
01 100k10
VOLTAG E NOISE DENSITY – nV/ Hz
100 1k 10k
TPC 6. Voltage Noise Spectral Density vs. Frequency (RTI)
(TA = 25C, RL = 2 k, V
S
= 15 V, unless otherwise noted.)
REV. A
AD8225
–7–
FREQUENCY – Hz
1000
100
01 10k10
VOLTAG E NOISE DENSITY – nV/ Hz
100 1k
TPC 7. Input Current Noise Spectral Density vs.
Frequency
100
90
10
0
1S
10
TIME – sec
5
NOISE – RTI – V
0
4
–4
–3
–2
–1
2
0
1
3
TPC 8. 0.1 Hz to 10 Hz Voltage Noise, RTI
100
90
10
0
10
TIME – sec
5
CURRENT NOISE – 2pA/div
0
–6
–4
–2
0
2
8
4
6
–8
1S
TPC 9. 0.1 Hz to 10 Hz Current Noise
FREQUENCY – Hz
130
110
30 1 100k10
CMR – dB
100 1k 10k
90
70
50
120
100
80
60
40
TPC 10. CMR vs. Frequency, RTI
TEMPERATURE – C
0.10
–0.10
–40 100–20
CMRR DRIFT – ppm/ C
020406080
0.08
–0.02
–0.04
–0.06
–0.08
0.04
0
0.06
0.02
TPC 11. CMRR vs. Temperature
OUTPUT VOLTAGE – V
15
–15
–15 15
–10
COMMON-MODE VOLTAGE – V
–5 0510
10
5
0
–5
–10
VS = 15V
VS = 5V
TPC 12. CMV Range vs. V
OUT
, Dual Supplies
REV. A–8–
AD8225
OUTPUT VOLTAGE – V
5
4
0051
COMMON-MODE VOLTAGE – V
234
3
2
1
VS = 5V
TPC 13. CMV vs. V
OUT
, Single Supply
FREQUENCY – Hz
140
120
0
0.1 1M1
PSRR – dB
10 100 1k
100
80
60
40
20
10k 100k
+VS
–VS
TPC 14. PSRR vs. Frequency, RTI
FREQUENCY – Hz
100 10M1k
GAIN – dB
10k 100k 1M
40
30
–60
20
10
0
–10
–20
–30
–40
–50
TPC 15. Small Signal Frequency Response,
V
OUT
= 200 mV p-p
FREQUENCY – Hz
100 10M1k
GAIN – dB
10k 100k 1M
40
30
–60
20
10
0
–10
–20
–30
–40
–50
TPC 16. Large Signal Frequency Response,
V
OUT
= 4 V p-p
+V
S
–0.0
–2.0 02010
INPUT VOLTAGE 5 – V
(REFERRED TO SUPPLY VOLTAGES)
–0.5
–1.0
–1.5
515
2.0
0
SUPPLY VOLTAGE V
1.5
1.0
0.5
2010515
–V
S
+0.0
TPC 17. Input Common Mode Voltage Range vs.
Supply Voltage
+V
S
0
–2.0 02016
OUTPUT VOLTAGE SWING – V
(REFERENCED TO SUPPLY VOLTAGES)
–0.5
–1.0
–1.5
4
–V
S
0
2.0
0
SUPPLY VOLTAGE V
1.5
1.0
0.5
14218610812
2016414218610812
R
L
= 10k
R
L
= 2k
R
L
= 10k
R
L
= 2k
TPC 18. Output Voltage Swing vs. Supply Voltage
and Load Resistance
REV. A
AD8225
–9–
LOAD RESISTANCE –
30
25
0
10 100k
100
OUTPUT VOLTAGE SWING – V p-p
1k
15
10
5
20
TPC 19. Output Voltage Swing vs. Load Resistance
100
90
0
OUTPUT (5V/DIV)
CH 2 = 10mV/DIV
TEST
CIRCUIT
OUTPUT
(0.001%/DIV)
HORIZ
(4s/DIV)
CH 1 = 5V/DIV
10
TPC 20. Large Signal Pulse Response and Settling
Time to 0.001%
100
90
10
0
OUTPUT
2
1
INPUT
CH 1 = 10mV, CH 2 = 20mV, H = 2s
TPC 21. Small Signal Pulse Response, C
L
= 100 pF
STEP SIZE – V
10
9
002051015
6
3
2
1
8
7
4
5
SETTLING TIME s
0.001%
0.01%
TPC 22. Settling Time vs. Step Size
100
90
10
0
100mV 2V
10
OUTPUT VOLTAGE – V
0
NONLINEARITY – ppm
–10
4
–4
–3
–2
–1
2
0
1
3
TPC 23. Gain Nonlinearity
SUPPLY VOLTAGE V
1.5
0.9
0.5 0202
SUPPLY CURRENT – mA
4681012 14 16 18
1.4
1.0
0.8
0.6
1.2
1.1
0.7
1.3
+85 C
+25 C
–40 C
TPC 24. I
SUPPLY
vs. V
SUPPLY
and Temperature
REV. A–10–
AD8225
AD8225
AD797
G = 5
G = 100
LPF SCOPE
G = 100
Test Circuit 1. 1 Hz to 10 Hz Voltage Noise Test
AD8225
AD829
2k
20
100
20k
4k
G = 5
G = 101
2k
Test Circuit 2. Settling Time to 0.01%
Test Circuits
REV. A
AD8225
–11–
V
B
+V
S
A1 A2
C2
R2
–IN Q2
C1 R1
+IN
Q1
3k
3k
15k
15k
V
REF
A3
+V
S
–V
S
+V
S
–V
S
+V
S
–V
S
OUT
+V
S
–V
S
Figure 3. Simplified Schematic
THEORY OF OPERATION
The AD8225 is a monolithic, three op amp instrumentation
amplifier. Laser wafer trimming and proprietary circuit tech-
niques enable the AD8225 to boast the lowest output offset
voltage and drift of any currently available in amp (150 µV
RTI), as well as a higher common-mode voltage range.
Referring to Figure 3, the input buffers consist of super-beta
NPN transistors Q1 and Q2, and op amps A1 and A2. The
transistors are compensated so that the bias currents are
extremely low, typically 100 pA or less. As a result, current noise
is also low, at 50 fA/Hz. The unity gain input buffers drive a
gain-of-five difference amplifier. Because the 3 k and 15 k
resistors are ratio matched, gain stability is better than 5 ppm/°C
over the rated temperature range.
The AD8225 also has five times the gain bandwidth of a typical
in amp. This wider GBW results from compensation at a fixed
gain of 5, which can be one fifth of that required if the amplifier
were compensated for unity gain.
High frequency performance is also enhanced by the innovative
pinout of the AD8225. Since Pins 1 and 8 are uncommitted,
Pin 1 may be connected to Pin 4. Since Pin 4 is also ac com-
mon, the stray capacitance at Pins 2 and 3 is balanced.
8
7
6
5
NC
+VS
VOUT
REF
AD8225
+IN
–IN
AC
GROUND
AC
GROUND
PIN 1 HAS NO INTERNAL CONNECTION
Figure 4. Pinout for Symmetrical Input Stray Capacitance
APPLICATIONS
Precision V-to-I Converter
When small analog voltages are transmitted across significant
distances, errors may develop due to ambient electrical noise,
stray capacitance, or series impedance effects. If the desired
voltage is converted to a current, however, the effects of ambient
noise are mitigated. All that is required is a voltage to current
conversion at the source, and an I-to-V conversion at the other
end to reverse the process.
Figure 5 illustrates how the AD8225 may be used as the trans-
mitter and receiver in a current loop system. The full-scale
output is 5 mA.
AD8225
2
3
5
6
47pF
9k
RSH
20
VSH
IOUT
AD8225
2
3
5
6
8
GND OR
REF V
1k
FULL SCALE
CURRENT = 5mA
eOUT
200mV
pk FS
eIN
200mV
pk FS
IOUT =
VSH
RSH
0.5 eIN
RSH
=
OP27
Figure 5. Precision Voltage-to-Current Converter
As noted in Figure 5, an additional op amp and four resistors are
required to complete the converter. The precision gain of 5 in the
AD8225s, used in the transmit and receive sections, preserves
the integrity of the desired signal, while the high frequency
common-mode performance at the receiver rejects noise on the
transmission line. The reference of the receiver may be connected
to local ground or the reference pin of an A/D converter (ADC).
Figure 6 shows bench measurements of the input and output
voltages, and output current of the circuit of Figure 5. The
transmission media is 10 feet of insulated hook-up wire for the
current drive and return lines.
e
IN
e
OUT
I
OUT
CH 1 = 100mV, CH 2 = 100mV, CH 3 = 10mA,
H = 200s
e
IN
= 398mV p-p,
e
OUT
= 398mV p-p,
I
OUT
= 10.3mA p-p
1
2
3
Figure 6. V-to-I Converter Waveforms (CH1: V
IN
,
CH2: V
OUT
, CH3: I
OUT
)
REV. A–12–
AD8225
Driving a High Resolution ADC
Most high precision ADCs feature differential analog inputs.
Differential inputs offer an inherent 6 dB improvement in S/N
ratio and resultant bit resolution. These advantages are easy to
realize using a pair of AD8225s.
AD8225s can be configured to drive an ADC with differential
inputs by using either single-ended or differential inputs to the
AD8225s. Figure 7 shows the circuit connections for a differen-
tial input. A single-ended input may be configured by connecting
the negative input terminal to ground.
2
3
2
3
6
6
5
5
AD8225
AD8225
OP177
1.25V
4.99k
4.99k
2.7nF
2.7nF
75
75
AD7675
100kSPS
5V
16 BITS
AD780
2.5V
RERERENCE
+IN
–IN
ALTERNATE
CONNECTION
FOR SE SOURCE
Figure 7. Driver for Differential ADC
The AD7675 ADC illustrated in Figure 7 is a SAR type converter.
When the input is sampled, the internal sample-and-hold capacitor
is charged to the input voltage level. Since the output of the
AD8225 cannot track the instantaneous current surge, a voltage
glitch develops. To source the momentary current surge, a
capacitor is connected from the A/D input terminal to ground.
Since the AD8225 cannot tolerate greater than approximately
100 pF of capacitance at its output, a 75 series resistor is
required at each in amp output to prevent oscillation.
Using the Reference Input
Note in the example in Figure 7 that Pin 5, the reference input, is
driven by a voltage source. This is because the reference pin is
internally connected to a 15 k resistor, which is carefully trimmed
to optimize common-mode rejection. Any additional resistance
connected to this node will unbalance the bridge network formed
by the two 3 k and two 15 k resistors, resulting in an error
voltage generated by common-mode voltages at the input pins.
AD8225 Used as an EKG Front End
The topology of the instrumentation amplifier has made it the
circuit configuration of choice for designers of EKG and other
low level biomedical amplifiers. CMRR and common-mode
voltage advantages of the instrumentation amplifier are tailor
made to meet the challenges of detecting minuscule cardiac
generated voltage levels in the presence of overwhelming levels
of noise and dc offset voltage. The subtracter circuit of the in
amp will extract and amplify low level signals that are virtually
obscured by the presence of high common-mode dc and ac
potentials.
A typical circuit block diagram of an EKG amplifier is shown in
Figure 8. Using discrete op amps in the in amp and gain stages,
the signal chain usually includes several filters, high voltage
protection, lead-select circuitry, patient lead buffering, and an
ADC. Designers who roll their own instrumentation amplifiers
must provide precision custom trimmed resistor networks and
well matched op amps.
The AD8225 instrumentation amplifier not only replaces all the
components shown in the highlighted block in Figure 8, but also
provides a solution to many of the difficult design problems
encountered in EKG front ends. Among these are patient gener-
ated errors from ac noise sources and errors generated by unequal
electrode potentials. Alone, these error voltages can exceed the
desired QRS complex by orders of magnitude.
INSTRUMENTATION AMPLIFIER
G = 3 TO 10
LEAD
SELECT,
HV
PROTECTION,
FILTERING
GAIN AND ADC
TOTA L G = 1000
PAT I ENT
ISOLATION
BARRIER
DIGITAL DATA
TO SYSTEM
MAINFRAME
A1
A2
A3
Figure 8. Block Diagram, EKG Monitor Front End Using Discrete Components
REV. A
AD8225
–13–
In the classical three op amp in amp topology shown in Figure 8,
gain is developed differentially between the two input amplifiers
A1 and A2, sacrificing CMV (common-mode voltage) range.
The gain of the in amp is typically 10 or less, and an additional
gain stage increases the overall gain to approximately 1000.
Gain developed in the input stage results in a trade-off in common-
mode voltage range, constraining the ability of the amplifier to
tolerate high dc electrode errors. Although the AD8225 is also
a three amplifier design, its gain of 5 is developed at the output
amplifier, improving the CMV range at the input. Using ±5V
supplies, the CMV range of the AD8225 is from 3.4 V to
+4 V, compared to 3.1 V to +3.8 V, a 7% improvement in
input headroom over conventional in amps with the same gain.
G = 5
AD8225
19.6k301
100
OP77
G = 200
G = 5
AD8225
19.6k301
100
OP77
G = 200
G = 5
AD8225
19.6k301
100
OP77
G = 200
Figure 9. EKG Monitor Front End
Figure 9 illustrates how an AD8225 may be used in an EKG
front end. In a low cost system, the AD8225 can be connected to
the patient. If buffers are required, the AD8225 can replace the
expensive precision resistor network and op amp.
Figure 10 shows test waveforms observed from the circuit of
Figure 9.
CH 1 = 2V, CH 2 = 2V, CH 3 = 2V, H = 200ms
RA-LA 1
LA-LL 2
RA-LL 3
Figure 10. EKG Waveform Using Circuit of Figure 9
Benefits of Fast Slew Rates
At 5 V/µs, the slew rate of the AD8225 is as fast as many op amp
circuits. This is an advantage in systems applications using multiple
sensors. For example, an analog multiplexer (see Figure 11) may
be used to select pairs of leads connected to several sensors. If
the AD8225 drives an ADC, the acquisition time is constrained
by the ability of the in amp to settle to a stable level after a new
set of leads is selected. Fast slew rates contribute greatly to
this function, especially if the difference in input levels is large.
AD8225
S1A
S1B
S2A
S2B
S3A
S3B
S4A
S4B
0.2V, 2V
ADG409 1
4
DA
DB
REF
Figure 11. Connection to an ADG409 Analog MUX
Figure 12 illustrates the response of an AD8225 connected to
an ADG409 analog multiplexer in the circuit shown in Figure 11
at two signal levels. Two of the four MUX inputs are connected
to test dc levels. The remaining two are at ground potential so
that the output slews as the inputs A0 and A1 are addressed. As
can be seen, the output response settles well within 4 µs of the
applied level.
CH 1 = 200mV, CH 2 = 2V, H = 500ns
LARGE SIGNAL
(2V/DIV)
SMALL SIGNAL
(200mV/DIV)
INPUT
SIGNAL
TRAN-
SITION
Figure 12. Slew Responses After MUX Selection
REV. A–14–
AD8225
Evaluation Board
Figure 13 is a schematic of an evaluation board available for the
AD8225. The board is shipped with an AD8225 already installed
and tested. The user need only connect power and an input to
conduct measurements. The supply may be configured for dual
A1
2
3
R3
100k*
R5
100k*
W3
W4
C1
0.1F
C3
0.1F
R4
100
R2
100
+IN
GND
–IN
+VS
C4
0.1F
OUTPUT
R8
5
41
C2
0.1F
W12
EXT_REF
W13
W11
W14
–VS
NOTES
REMOVE W3 AND W4 FOR AC COUPLING
*INSTALL FOR AC COUPLING
+VS
GND
–VS
C12
10F, 25V
C11
10F, 25V
W7
W6
+VAUX
–VAUX
C9
0.1F
4
673
2
A1
C10
0.1F
–VAUX
OFFSET
ADJ R1
10k
+VAUX
R9
5.9k, 1%
R10
5.9k, 1%
C7
0.1F
C8
0.1F
CS2
J500
240A
CS1
J500
240A
–VAUX
AD707JN
USER-SUPPLIED
7
6
Figure 13. Evaluation Board Schematic
or single supplies, and the input may be dc- or ac-coupled. A
circuit is provided on the board so that the user can zero the
output offset. If desired, a reference may be applied from an
external voltage source.
REV. A
AD8225
–15–
OUTLINE DIMENSIONS
8-Lead Standard Small Outline Package (SOIC)
(RN-8)
Dimensions shown in millimeters and (inches)
0.25 (0.0098)
0.19 (0.0075)
1.27 (0.0500)
0.41 (0.0160)
0.50 (0.0196)
0.25 (0.0099)
45
8
0
1.75 (0.0688)
1.35 (0.0532)
SEATING
PLANE
0.25 (0.0098)
0.10 (0.0040)
85
41
5.00 (0.1968)
4.80 (0.1890)
4.00 (0.1574)
3.80 (0.1497)
1.27 (0.0500)
BSC
6.20 (0.2440)
5.80 (0.2284)
0.51 (0.0201)
0.33 (0.0130)
COPLANARITY
0.10
CONTROLLING DIMENSIONS ARE IN MILLIMETERS; INCH DIMENSIONS
(IN PARENTHESES) ARE ROUNDED-OFF MILLIMETER EQUIVALENTS FOR
REFERENCE ONLY AND ARE NOT APPROPRIATE FOR USE IN DESIGN
COMPLIANT TO JEDEC STANDARDS MS-012AA
REV. A
C02771–0–2/03(A)
PRINTED IN U.S.A.
–16–
AD8225
Revision History
Location Page
2/03—Data Sheet changed from REV. 0 to REV. A.
Updated ORDERING GUIDE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Change to TPC 10 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
Change to TPC 20 caption . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Edit to Precision V-to-I Converter section . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
OUTLINE DIMENSIONS updated . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
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